Sometimes the best indoor photos are taken without flash. Natural lighting is, well, so much more natural. The photo on the left is taken at ISO 200 with my built-in flash. The colors are accurately represented. And the noise (grain) is tight and sharp. But compare it to the photo on the left. Look at how you can see the night light and almost read the numbers on the clock radio? You can even see the wood floor in the room. That's because I did not use a flash and boosted my ISO considerably in order to get enough light to really make this photo work. I boosted the ISO all the way up to 1600. And the image is lit well because I used a very slow shutter speed, which allowed the ambient light in the room (the light in the shot, the light in the room behind me and the lights along the curtains) to record onto the CCD. The shot is certainly grainy, and the color is not as accurate as in the image on the left, but given a choice, I definitely prefer the right side. It has more dimension and life. Boosting your ISO makes the chip more sensitive to light, so you can shoot in lower light and still get the shot. In this case, my light level was so low, that even at ISO 1600 and with my aperture opened all of the way to let in the maximum amount of light through the lens, my shutter speed was very slow-just one quarter of a second (1/4). So I had my VC image stabilization feature on my lens switched on for this shot to be sure I could hand-hold the camera without getting blur.(Left: 18mm; F/9; 1/60th sec; ISO 200; flash fired. Right: 18mm; F/6.3; 1/4th sec; ISO 1600; no flash).